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Prion‐like mechanisms in neurodegenerative disease: Implications for Huntington's disease therapy
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG repeat expansions in the huntingtin gene resulting in the synthesis of a misfolded form of the huntingtin protein (mHTT) which is toxic. The current treatments for HD are only palliative. Some of the p...
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| Publicado no: | Stem Cells Transl Med |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7180288/ https://ncbi.nlm.nih.gov/pubmed/31997581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0248 |
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