Engineering a responsive DNA triple helix into an octahedral DNA nanostructure for a reversible opening/closing switching mechanism: a computational and experimental integrated study

We propose an experimental and simulative approach to study the effect of integrating a DNA functional device into a large-sized DNA nanostructure. We selected, as a test bed, a well-known and characterized pH-dependent clamp-switch, based on a parallel DNA triple helix, to be integrated into a trun...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Ottaviani, Alessio, Iacovelli, Federico, Idili, Andrea, Falconi, Mattia, Ricci, Francesco, Desideri, Alessandro
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Chemical Biology and Nucleic Acid Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212788/
https://ncbi.nlm.nih.gov/pubmed/30247614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky857
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items