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Stability of an RNA•DNA–DNA triple helix depends on base triplet composition and length of the RNA third strand

Recent studies suggest noncoding RNAs interact with genomic DNA, forming an RNA•DNA–DNA triple helix that regulates gene expression. However, base triplet composition of pyrimidine motif RNA•DNA–DNA triple helices is not well understood beyond the canonical U•A–T and C•G–C base triplets. Using nativ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Kunkler, Charlotte N, Hulewicz, Jacob P, Hickman, Sarah C, Wang, Matthew C, McCown, Phillip J, Brown, Jessica A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698731/
https://ncbi.nlm.nih.gov/pubmed/31265072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz573
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