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Stability of an RNA•DNA–DNA triple helix depends on base triplet composition and length of the RNA third strand

Recent studies suggest noncoding RNAs interact with genomic DNA, forming an RNA•DNA–DNA triple helix that regulates gene expression. However, base triplet composition of pyrimidine motif RNA•DNA–DNA triple helices is not well understood beyond the canonical U•A–T and C•G–C base triplets. Using nativ...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Kunkler, Charlotte N, Hulewicz, Jacob P, Hickman, Sarah C, Wang, Matthew C, McCown, Phillip J, Brown, Jessica A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698731/
https://ncbi.nlm.nih.gov/pubmed/31265072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz573
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