RbpA relaxes promoter selectivity of M. tuberculosis RNA polymerase

The transcriptional activator RbpA associates with Mycobacterium tuberculosis RNA polymerase (MtbRNAP) during transcription initiation, and stimulates formation of the MtbRNAP-promoter open complex (RPo). Here, we explored the influence of promoter motifs on RbpA-mediated activation of MtbRNAP conta...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Sudalaiyadum Perumal, Ayyappasamy, Vishwakarma, Rishi Kishore, Hu, Yangbo, Morichaud, Zakia, Brodolin, Konstantin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212719/
https://ncbi.nlm.nih.gov/pubmed/30102406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky714
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