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Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the σ(A)-containing RNA polymerase holoenzyme
RbpA is an RNA polymerase (RNAP)-binding protein whose presence increases the tolerance levels of Mycobacteria to the first-line anti-tuberculosis drug rifampicin by an unknown mechanism. Here, we show that the role of Mycobacterium tuberculosis RbpA in resistance is indirect because it does not aff...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413145/ https://ncbi.nlm.nih.gov/pubmed/22570422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks346 |
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