The SGK3-triggered ubiquitin–proteasome degradation of podocalyxin (PC) and ezrin in podocytes was associated with the stability of the PC/ezrin complex

Podocyte damage is commonly accompanied by destabilization of the podocalyxin (PC)/ezrin complex. Serum- and glucocorticoid-inducible kinase 3 (SGK3) plays a role in the maintenance of podocyte function, but the details of this role are poorly understood. Herein we demonstrated that SGK3 and its dow...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Yuan, Ya-Pei, Zhao, Hong, Peng, Li-Qin, Li, Zi-Fang, Liu, Song, Yuan, Cheng-Yan, Mwamunyi, Mercy-Julian, Pearce, David, Yao, Li-Jun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212497/
https://ncbi.nlm.nih.gov/pubmed/30385740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1161-1
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