NGX6a Is Degraded through a Proteasome-dependent Pathway without Ubiquitination Mediated by Ezrin, a Cytoskeleton-Membrane Linker

Our previous study demonstrated that the NGX6b gene acts as a suppressor in the invasion and migration of nasopharyngeal carcinoma (NPC). Recently, we identified the novel isoform NGX6a, which is longer than NGX6b. In this study, we first found that NGX6a was degraded in NPC cells and that this degr...

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Vydáno v:J Biol Chem
Hlavní autoři: Wang, Li, Li, Xiaoling, Xiang, Bo, Zhou, Ming, Li, Xiayu, Xiong, Wei, Niu, Man, Wei, Pingpin, Wang, Zeyou, Wang, Heran, Chen, Pan, Shen, Shourong, Peng, Shuping, Li, Guiyuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276843/
https://ncbi.nlm.nih.gov/pubmed/25378401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.584771
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