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Phase 2b study of evocalcet (KHK7580), a novel calcimimetic, in Japanese patients with secondary hyperparathyroidism undergoing hemodialysis: A randomized, double-blind, placebo-controlled, dose-finding study

BACKGROUND: Evocalcet has been developed as a new calcimimetic agent for hemodialysis (HD) patients with secondary hyperparathyroidism (HDSHPT), eliciting fewer gastrointestinal symptoms and drug interactions. We evaluated the efficacy, safety, and optimal starting dose of evocalcet in HDSHPT. METHO...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Akizawa, Tadao, Shimazaki, Ryutaro, Fukagawa, Masafumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209414/
https://ncbi.nlm.nih.gov/pubmed/30379826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204896
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