Pharmacokinetics, Pharmacodynamics, and Safety of the Novel Calcimimetic Agent Evocalcet in Healthy Japanese Subjects: First-in-Human Phase I Study

BACKGROUND AND OBJECTIVES: Evocalcet is a novel calcimimetic agent with potential to improve the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. This study aimed to determine the pharmacokinetics, pharmacodynamics, and safety of evocalcet in healthy Japanese subje...

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Bibliographic Details
Published in:Clin Drug Investig
Main Authors: Akizawa, Tadao, Shimazaki, Ryutaro, Shiramoto, Masanari, Fukagawa, Masafumi
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2018
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Original Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182462/
https://ncbi.nlm.nih.gov/pubmed/30168004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-018-0687-4
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