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Pharmacokinetics, Pharmacodynamics, and Safety of the Novel Calcimimetic Agent Evocalcet in Healthy Japanese Subjects: First-in-Human Phase I Study

BACKGROUND AND OBJECTIVES: Evocalcet is a novel calcimimetic agent with potential to improve the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. This study aimed to determine the pharmacokinetics, pharmacodynamics, and safety of evocalcet in healthy Japanese subje...

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Publicado en:Clin Drug Investig
Main Authors: Akizawa, Tadao, Shimazaki, Ryutaro, Shiramoto, Masanari, Fukagawa, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182462/
https://ncbi.nlm.nih.gov/pubmed/30168004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-018-0687-4
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