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Phase 2b study of evocalcet (KHK7580), a novel calcimimetic, in Japanese patients with secondary hyperparathyroidism undergoing hemodialysis: A randomized, double-blind, placebo-controlled, dose-finding study

BACKGROUND: Evocalcet has been developed as a new calcimimetic agent for hemodialysis (HD) patients with secondary hyperparathyroidism (HDSHPT), eliciting fewer gastrointestinal symptoms and drug interactions. We evaluated the efficacy, safety, and optimal starting dose of evocalcet in HDSHPT. METHO...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Akizawa, Tadao, Shimazaki, Ryutaro, Fukagawa, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209414/
https://ncbi.nlm.nih.gov/pubmed/30379826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204896
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