A hydroquinone-specific screening system for directed P450 evolution

The direct hydroxylation of benzene to hydroquinone (HQ) under mild reaction conditions is a challenging task for chemical catalysts. Cytochrome P450 (CYP) monooxygenases are known to catalyze the oxidation of a variety of aromatic compounds with atmospheric dioxygen. Protein engineering campaigns l...

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Bibliografiske detaljer
Udgivet i:Appl Microbiol Biotechnol
Main Authors: Weingartner, Alexandra M., Sauer, Daniel F., Dhoke, Gaurao V., Davari, Mehdi D., Ruff, Anna Joëlle, Schwaneberg, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2018
Fag:
Biotechnologically Relevant Enzymes and Proteins
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208966/
https://ncbi.nlm.nih.gov/pubmed/30191291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-018-9328-3
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