A comparison of qPCR and ddPCR used for quantification of the JAK2 V617F allele burden in Ph negative MPNs

Philadelphia-negative myeloproliferative neoplasms (MPNs) are a diverse group of diseases whose common feature is the presence of V617F mutation of the JAK2 gene. In the era of novel therapeutic strategies in MPNs, such as JAK-inhibitor therapy, there is a growing need for establishing high sensitiv...

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Vydáno v:Ann Hematol
Hlavní autoři: Link-Lenczowska, Dorota, Pallisgaard, Niels, Cordua, Sabrina, Zawada, Magdalena, Czekalska, Sylwia, Krochmalczyk, Dorota, Kanduła, Zuzanna, Sacha, Tomasz
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208664/
https://ncbi.nlm.nih.gov/pubmed/30056580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-018-3451-1
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