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Asiatic acid ameliorates CCl(4)-induced liver fibrosis in rats: involvement of Nrf2/ARE, NF-κB/IκBα, and JAK1/STAT3 signaling pathways

PURPOSE: Currently, there are no effective therapies for liver fibrosis; hence, the development of anti-liver fibrosis agents is urgently needed. Here, we attempted to investigate the therapeutic effect and mechanism of asiatic acid (AA) on liver fibrosis, mainly focusing on the impact of AA on nucl...

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Dades bibliogràfiques
Publicat a:Drug Des Devel Ther
Autors principals: Fan, Jie, Chen, Qingshan, Wei, Liwen, Zhou, Xiaoming, Wang, Rong, Zhang, Hai
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208532/
https://ncbi.nlm.nih.gov/pubmed/30464391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S179876
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