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Asiatic acid ameliorates CCl(4)-induced liver fibrosis in rats: involvement of Nrf2/ARE, NF-κB/IκBα, and JAK1/STAT3 signaling pathways

PURPOSE: Currently, there are no effective therapies for liver fibrosis; hence, the development of anti-liver fibrosis agents is urgently needed. Here, we attempted to investigate the therapeutic effect and mechanism of asiatic acid (AA) on liver fibrosis, mainly focusing on the impact of AA on nucl...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Fan, Jie, Chen, Qingshan, Wei, Liwen, Zhou, Xiaoming, Wang, Rong, Zhang, Hai
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208532/
https://ncbi.nlm.nih.gov/pubmed/30464391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S179876
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