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Multimodal antidepressant vortioxetine causes analgesia in a mouse model of chronic neuropathic pain
Vortioxetine is a multimodal antidepressant that potently antagonizes 5-HT3 serotonin receptors, inhibits the high-affinity serotonin transporter, activates 5-HT1A and 5-HT1B receptors, and antagonizes 5-HT1D and 5-HT7 receptors. 5-HT3 receptors largely mediate the hyperalgesic activity of serotonin...
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| Gepubliceerd in: | Mol Pain |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
SAGE Publications
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6207957/ https://ncbi.nlm.nih.gov/pubmed/30289053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806918808987 |
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