Multimodal antidepressant vortioxetine causes analgesia in a mouse model of chronic neuropathic pain

Vortioxetine is a multimodal antidepressant that potently antagonizes 5-HT3 serotonin receptors, inhibits the high-affinity serotonin transporter, activates 5-HT1A and 5-HT1B receptors, and antagonizes 5-HT1D and 5-HT7 receptors. 5-HT3 receptors largely mediate the hyperalgesic activity of serotonin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Pain
Main Authors: Zuena, Anna Rita, Maftei, Daniela, Alemà, Giovanni Sebastiano, Dal Moro, Francesca, Lattanzi, Roberta, Casolini, Paola, Nicoletti, Ferdinando
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207957/
https://ncbi.nlm.nih.gov/pubmed/30289053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806918808987
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker