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NFκB Sensing IL-4 Secreting Mesenchymal Stem Cells Mitigate the Proinflammatory Response of Macrophages Exposed to Polyethylene Wear Particles
Total joint replacement (TJR) is a highly effective treatment for patients with end-stage arthritis. Pro-inflammatory macrophages (M1) mediate wear particle-associated inflammation and bone loss. Anti-inflammatory macrophages (M2) help resolve tissue damage and favor bone regeneration. Mesenchymal s...
Shranjeno v:
| izdano v: | J Biomed Mater Res A |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6207939/ https://ncbi.nlm.nih.gov/pubmed/30084534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.36504 |
| Oznake: |
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