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Molecular weight of surface immobilized hyaluronic acid influences CD44-mediated binding of gastric cancer cells

The physiological importance of the interactions between hyaluronic acid (HA) and its main membrane receptor, CD44, in pathological processes, e.g. cancer, is well recognized. However, these interactions are mainly studied in solution, whereas HA in the extracellular matrix (ECM) is partially immobi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Amorim, Sara, da Costa, Diana Soares, Freitas, Daniela, Reis, Celso A., Reis, Rui L., Pashkuleva, Iva, Pires, Ricardo A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207784/
https://ncbi.nlm.nih.gov/pubmed/30375477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34445-0
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