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Identification and antitumor activity of a novel inhibitor of the NIMA-related kinase NEK6
The NIMA (never in mitosis, gene A)-related kinase-6 (NEK6), which is implicated in cell cycle control and plays significant roles in tumorigenesis, is an attractive target for the development of novel anti-cancer drugs. Here we describe the discovery of a potent ATP site-directed inhibitor of NEK6...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6207720/ https://ncbi.nlm.nih.gov/pubmed/30375481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34471-y |
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