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The NIMA-family kinase, Nek1 affects the stability of centrosomes and ciliogenesis

BACKGROUND: Mutations in Nek1 (NIMA-Related Kinase 1) are causal in the murine models of polycystic kidney disease kat and kat(2J). The Neks are known as cell cycle kinases, but recent work in protists has revealed that in addition to roles in the regulation of cell cycle progression, some Neks also...

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Detalhes bibliográficos
Main Authors: White, Mark C, Quarmby, Lynne M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442590/
https://ncbi.nlm.nih.gov/pubmed/18533026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-9-29
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