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A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

Nek2, a mammalian protein kinase of unknown function, is closely related to the mitotic regulator NIMA of Aspergillus nidulans. Here we show by both immunofluorescence microscopy and biochemical fractionation that human Nek2 localizes to the centrosome. Centrosome association occurs throughout the c...

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Main Authors: Fry, A M, Meraldi, P, Nigg, E A
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170398/
https://ncbi.nlm.nih.gov/pubmed/9430639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.2.470
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