Direct cysteine sulfenylation drives activation of the Src kinase

The Src kinase controls aspects of cell biology and its activity is regulated by intramolecular structural changes induced by protein interactions and tyrosine phosphorylation. Recent studies indicate that Src is additionally regulated by redox-dependent mechanisms, involving oxidative modification(...

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Pubblicato in:Nat Commun
Autori principali: Heppner, David E., Dustin, Christopher M., Liao, Chenyi, Hristova, Milena, Veith, Carmen, Little, Andrew C., Ahlers, Bethany A., White, Sheryl L., Deng, Bin, Lam, Ying-Wai, Li, Jianing, van der Vliet, Albert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207713/
https://ncbi.nlm.nih.gov/pubmed/30375386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06790-1
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