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Probing Light Chain Mutation Effects on Thrombin via Molecular Dynamics Simulations and Machine Learning
Thrombin is a key component for chemotherapeutic and antithrombotic therapy development. As the physiologic and pathologic roles of the light chain still remain vague, here, we continue previous efforts to understand the impacts of the disease-associated single deletion of LYS9 in the light chain. B...
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| Vydáno v: | J Biomol Struct Dyn |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6207482/ https://ncbi.nlm.nih.gov/pubmed/29471734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2018.1445032 |
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