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Mechanistic insights into thrombin’s switch between “slow” and “fast” forms()
Thrombin is a multifunctional enzyme that plays an important role in blood coagulation, cell growth, and metastasis. Depending upon the binding of sodium ions, thrombin presents significantly different enzymatic activities. In the environment with sodium ions, thrombin is highly active in cleaving t...
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Publicado no: | Phys Chem Chem Phys |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5719506/ https://ncbi.nlm.nih.gov/pubmed/28849814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cp03671j |
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