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Mechanistic insights into thrombin’s switch between “slow” and “fast” forms()

Thrombin is a multifunctional enzyme that plays an important role in blood coagulation, cell growth, and metastasis. Depending upon the binding of sodium ions, thrombin presents significantly different enzymatic activities. In the environment with sodium ions, thrombin is highly active in cleaving t...

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Bibliografiska uppgifter
I publikationen:Phys Chem Chem Phys
Huvudupphovsmän: Xiao, Jiajie, Melvin, Ryan L., Salsbury, Freddie R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719506/
https://ncbi.nlm.nih.gov/pubmed/28849814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cp03671j
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