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Mechanistic insights into thrombin’s switch between “slow” and “fast” forms()

Thrombin is a multifunctional enzyme that plays an important role in blood coagulation, cell growth, and metastasis. Depending upon the binding of sodium ions, thrombin presents significantly different enzymatic activities. In the environment with sodium ions, thrombin is highly active in cleaving t...

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Bibliografiske detaljer
Udgivet i:Phys Chem Chem Phys
Main Authors: Xiao, Jiajie, Melvin, Ryan L., Salsbury, Freddie R.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719506/
https://ncbi.nlm.nih.gov/pubmed/28849814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cp03671j
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