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Na(+)-binding modes involved in thrombin’s allosteric response as revealed by molecular dynamics simulations, correlation networks and Markov modeling
The monovalent sodium ion (Na(+)) is a critical modulator of thrombin. However, the mechanism of thrombin’s activation by Na(+) has been widely debated for more than twenty years. Details of the linkage between thrombin and Na(+) remain vague due to limited temporal and spatial resolution in experim...
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| Publicado no: | Phys Chem Chem Phys |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6993936/ https://ncbi.nlm.nih.gov/pubmed/30724273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cp07293k |
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