Phosphodiesterase-5 is Elevated in Failing Single Ventricle Myocardium and Affects Cardiomyocyte Remodeling in vitro

BACKGROUND: Single ventricle congenital heart disease (SV) is fatal without intervention and eventual heart failure (HF) is a major cause of morbidity and mortality. While there are no proven medical therapies for the treatment or prevention of HF in the SV population, phosphodiesterase-5 inhibitors...

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Vydáno v:Circ Heart Fail
Hlavní autoři: Garcia, Anastacia M., Nakano, Stephanie J., Karimpour-Fard, Anis, Nunley, Karin, Blain-Nelson, Penny, Stafford, Natalie M., Stauffer, Brian L, Sucharov, Carmen C., Miyamoto, Shelley D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206883/
https://ncbi.nlm.nih.gov/pubmed/30354365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.004571
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