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Age-Related Differences in Phosphodiesterase Activity and Effects of Chronic Phosphodiesterase Inhibition in Idiopathic Dilated Cardiomyopathy

BACKGROUND: Despite the application of proven adult heart failure (HF) therapies to children with idiopathic dilated cardiomyopathy (IDC), prognosis remains poor. Clinical experience with phosphodiesterase 3 inhibitors (PDE3i) in pediatric IDC patients, however, demonstrates improved HF symptoms wit...

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Bibliografiska uppgifter
I publikationen:Circ Heart Fail
Huvudupphovsmän: Nakano, Stephanie J., Miyamoto, Shelley D., Movsesian, Matthew, Nelson, Penny, Stauffer, Brian L., Sucharov, Carmen C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303519/
https://ncbi.nlm.nih.gov/pubmed/25278000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001218
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