Cardiac Adenylyl Cyclase and Phosphodiesterase Expression Profiles Vary by Age, Disease, and Chronic Phosphodiesterase Inhibitor Treatment

BACKGROUND: Pediatric heart failure (HF) patients have a suboptimal response to traditional HF medications, although phosphodiesterase-3 inhibition (PDE3i) has been used with greater success than in the adult HF population. We hypothesized that molecular alterations specific to children with HF and...

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Detalhes bibliográficos
Publicado no:J Card Fail
Main Authors: NAKANO, STEPHANIE J., SUCHAROV, JULIANA, VAN DUSEN, ROBERT, CECIL, MACKENZIE, NUNLEY, KARIN, WICKERS, SEAN, KARIMPUR-FARD, ANIS, STAUFFER, BRIAN L., MIYAMOTO, SHELLEY D., SUCHAROV, CARMEN C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384997/
https://ncbi.nlm.nih.gov/pubmed/27427220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2016.07.429
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