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Sphingosine Kinase Activates the Mitochondrial Unfolded Protein Response and Is Targeted to Mitochondria by Stress
The mitochondrial unfolded protein response (UPR(mt)) is critical for maintaining mitochondrial protein homeostasis in response to mitochondrial stress, but early steps in UPR(mt) activation are not well understood. Here, we report a function for SPHK-1 sphingosine kinase in activating the UPR(mt) i...
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| 出版年: | Cell Rep |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6206875/ https://ncbi.nlm.nih.gov/pubmed/30208318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.037 |
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