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Sphingosine Kinase Activates the Mitochondrial Unfolded Protein Response and Is Targeted to Mitochondria by Stress
The mitochondrial unfolded protein response (UPR(mt)) is critical for maintaining mitochondrial protein homeostasis in response to mitochondrial stress, but early steps in UPR(mt) activation are not well understood. Here, we report a function for SPHK-1 sphingosine kinase in activating the UPR(mt) i...
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| Publicado no: | Cell Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6206875/ https://ncbi.nlm.nih.gov/pubmed/30208318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.037 |
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