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DNA-corralled nanodiscs for the structural and functional characterization of membrane proteins and viral entry

Here we present a modular method for manufacturing large-sized nanodiscs using DNA-origami barrels as scaffolding corrals. Large-sized nanodiscs can be produced by first decorating the inside of DNA barrels with small lipid-bilayer nanodiscs, which open up when adding extra lipid to form large nanod...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Zhao, Zhao, Zhang, Meng, Hogle, James M., Shih, William M., Wagner, Gerhard, Nasr, Mahmoud L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206850/
https://ncbi.nlm.nih.gov/pubmed/30094995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b04638
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