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Covalently circularized nanodiscs for studying membrane proteins and viral entry
We engineered covalently circularized nanodiscs (cNDs) with enhanced stability, defined diameter sizes and tunable shapes. Reconstitution into cNDs enhanced the quality of NMR spectra for both VDAC-1, a beta-barrel membrane protein, and the G protein-coupled receptor NTR1, an alpha-helical membrane...
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| Veröffentlicht in: | Nat Methods |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5199620/ https://ncbi.nlm.nih.gov/pubmed/27869813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4079 |
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