Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma

Glioblastoma (GBM) is one of the most common, deadly, and difficult-to-treat adult brain tumors. Surgical removal of the tumor, followed by radiotherapy (RT) and temozolomide (TMZ) administration, is the current treatment modality, but this regimen only modestly improves overall patient survival. In...

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Vydáno v:Front Oncol
Hlavní autoři: Harder, Bryan G., Blomquist, Mylan R., Wang, Junwen, Kim, Anthony J., Woodworth, Graeme F., Winkles, Jeffrey A., Loftus, Joseph C., Tran, Nhan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206841/
https://ncbi.nlm.nih.gov/pubmed/30406029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00462
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