Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma

Glioblastoma (GBM) is one of the most common, deadly, and difficult-to-treat adult brain tumors. Surgical removal of the tumor, followed by radiotherapy (RT) and temozolomide (TMZ) administration, is the current treatment modality, but this regimen only modestly improves overall patient survival. In...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Harder, Bryan G., Blomquist, Mylan R., Wang, Junwen, Kim, Anthony J., Woodworth, Graeme F., Winkles, Jeffrey A., Loftus, Joseph C., Tran, Nhan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206841/
https://ncbi.nlm.nih.gov/pubmed/30406029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00462
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