The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance

BACKGROUND: Glioblastoma (GBM) is a difficult to treat brain cancer that nearly uniformly recurs, and recurrent tumors are largely therapy resistant. Our prior work has demonstrated an important role for the tumor necrosis factor–like weak inducer of apoptosis (TWEAK) receptor fibroblast growth fact...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Hersh, David S, Harder, Bryan G, Roos, Alison, Peng, Sen, Heath, Jonathan E, Legesse, Teklu, Kim, Anthony J, Woodworth, Graeme F, Tran, Nhan L, Winkles, Jeffrey A
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Basic and Translational Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140775/
https://ncbi.nlm.nih.gov/pubmed/29897522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy063
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