The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance

BACKGROUND: Glioblastoma (GBM) is a difficult to treat brain cancer that nearly uniformly recurs, and recurrent tumors are largely therapy resistant. Our prior work has demonstrated an important role for the tumor necrosis factor–like weak inducer of apoptosis (TWEAK) receptor fibroblast growth fact...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Hersh, David S, Harder, Bryan G, Roos, Alison, Peng, Sen, Heath, Jonathan E, Legesse, Teklu, Kim, Anthony J, Woodworth, Graeme F, Tran, Nhan L, Winkles, Jeffrey A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140775/
https://ncbi.nlm.nih.gov/pubmed/29897522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy063
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