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Activation of Electrophile/Nucleophile Pair by a Nucleophilic and Electrophilic Solvation in a S(N)Ar Reaction
Nucleophilic aromatic substitution reactions of 4-chloroquinazoline toward aniline and hydrazine were used as a model system to experimentally show that a substrate bearing heteroatoms on the aromatic ring as substituent is able to establish intramolecular hydrogen bond which may be activated by the...
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| Veröffentlicht in: | Front Chem |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6206274/ https://ncbi.nlm.nih.gov/pubmed/30406087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00509 |
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