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Homeostasis of protein and mRNA concentrations in growing cells

Many experiments show that the numbers of mRNA and protein are proportional to the cell volume in growing cells. However, models of stochastic gene expression often assume constant transcription rate per gene and constant translation rate per mRNA, which are incompatible with these experiments. Here...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lin, Jie, Amir, Ariel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206055/
https://ncbi.nlm.nih.gov/pubmed/30374016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06714-z
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