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Protein products of nonstop mRNA disrupt nucleolar homeostasis
Stalled mRNA translation results in the production of incompletely synthesized proteins that are targeted for degradation by ribosome-associated quality control (RQC). Here we investigated the fate of defective proteins translated from stall-inducing, nonstop mRNA that escape ubiquitylation by the R...
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| Pubblicato in: | Cell Stress Chaperones |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Netherlands
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8065075/ https://ncbi.nlm.nih.gov/pubmed/33619693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-021-01200-w |
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