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Homeostasis of protein and mRNA concentrations in growing cells

Many experiments show that the numbers of mRNA and protein are proportional to the cell volume in growing cells. However, models of stochastic gene expression often assume constant transcription rate per gene and constant translation rate per mRNA, which are incompatible with these experiments. Here...

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Publicat a:Nat Commun
Autors principals: Lin, Jie, Amir, Ariel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206055/
https://ncbi.nlm.nih.gov/pubmed/30374016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06714-z
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