Candida albicans gains azole resistance by altering sphingolipid composition

Fungal infections by drug-resistant Candida albicans pose a global public health threat. However, the pathogen’s diploid genome greatly hinders genome-wide investigations of resistance mechanisms. Here, we develop an efficient piggyBac transposon-mediated mutagenesis system using stable haploid C. a...

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Publicat a:Nat Commun
Autors principals: Gao, Jiaxin, Wang, Haitao, Li, Zeyao, Wong, Ada Hang-Heng, Wang, Yi-Zheng, Guo, Yahui, Lin, Xin, Zeng, Guisheng, Liu, Haoping, Wang, Yue, Wang, Jianbin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206040/
https://ncbi.nlm.nih.gov/pubmed/30374049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06944-1
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