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Candida albicans gains azole resistance by altering sphingolipid composition
Fungal infections by drug-resistant Candida albicans pose a global public health threat. However, the pathogen’s diploid genome greatly hinders genome-wide investigations of resistance mechanisms. Here, we develop an efficient piggyBac transposon-mediated mutagenesis system using stable haploid C. a...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6206040/ https://ncbi.nlm.nih.gov/pubmed/30374049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06944-1 |
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