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Pph3 Dephosphorylation of Rad53 Is Required for Cell Recovery from MMS-Induced DNA Damage in Candida albicans

The pathogenic fungus Candida albicans switches from yeast growth to filamentous growth in response to genotoxic stresses, in which phosphoregulation of the checkpoint kinase Rad53 plays a crucial role. Here we report that the Pph3/Psy2 phosphatase complex, known to be involved in Rad53 dephosphoryl...

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Detalhes bibliográficos
Main Authors: Wang, Haitao, Gao, Jiaxin, Li, Wanjie, Wong, Ada Hang-Heng, Hu, Kangdi, Chen, Kun, Wang, Yue, Sang, Jianli
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351423/
https://ncbi.nlm.nih.gov/pubmed/22606354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037246
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