The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth via triggering autophagy

Neddylation is a post-translational protein modification process. MLN4924 is a newly discovered pharmaceutical neddylation inhibitor that suppresses cancer growth with several cancer types. In our study, we first investigated the effect of MLN4924 on colon cancer cells (HCT116 and HT29). MLN4924 sig...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Korean J Physiol Pharmacol
Egile Nagusiak: Lv, Yongzhu, Li, Bing, Han, Kunna, Xiao, Yang, Yu, Xianjun, Ma, Yong, Jiao, Zhan, Gao, Jianjun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205944/
https://ncbi.nlm.nih.gov/pubmed/30402022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2018.22.6.617
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