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The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth via triggering autophagy
Neddylation is a post-translational protein modification process. MLN4924 is a newly discovered pharmaceutical neddylation inhibitor that suppresses cancer growth with several cancer types. In our study, we first investigated the effect of MLN4924 on colon cancer cells (HCT116 and HT29). MLN4924 sig...
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| Publicado no: | Korean J Physiol Pharmacol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Physiological Society and The Korean Society of Pharmacology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6205944/ https://ncbi.nlm.nih.gov/pubmed/30402022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2018.22.6.617 |
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