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Mitochondrial dysfunction reduces the activity of KIR2.1 K(+) channel in myoblasts via impaired oxidative phosphorylation

Myoblast fusion depends on mitochondrial integrity and intracellular Ca(2+) signaling regulated by various ion channels. In this study, we investigated the ionic currents associated with [Ca(2+)](i) regulation in normal and mitochondrial DNA-depleted (ρ0) L6 myoblasts. The ρ0 myoblasts showed impair...

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Detalhes bibliográficos
Publicado no:Korean J Physiol Pharmacol
Main Authors: Woo, JooHan, Kim, Hyun Jong, Nam, Yu Ran, Kim, Yung Kyu, Lee, Eun Ju, Choi, Inho, Kim, Sung Joon, Lee, Wan, Nam, Joo Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205933/
https://ncbi.nlm.nih.gov/pubmed/30402030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2018.22.6.697
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