Luteolin reduces fluid hypersecretion by inhibiting TMEM16A in interleukin-4 treated Calu-3 airway epithelial cells

Rhinorrhea in allergic rhinitis (AR) is characterized by the secretion of electrolytes in the nasal discharge. The secretion of Cl(–) and HCO(3)(–) is mainly regulated by cystic fibrosis transmembrane conductance regulator (CFTR) or via the calcium-activated Cl(–) channel anoctamin-1 (ANO1) in nasal...

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Vydáno v:Korean J Physiol Pharmacol
Hlavní autoři: Kim, Hyun Jong, Woo, JooHan, Nam, Yu-Ran, Seo, Yohan, Namkung, Wan, Nam, Joo Hyun, Kim, Woo Kyung
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Physiological Society and The Korean Society of Pharmacology 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317179/
https://ncbi.nlm.nih.gov/pubmed/32587127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2020.24.4.329
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