Age-specific genome-wide association study in glioblastoma identifies increased proportion of ‘lower grade glioma’-like features associated with younger age

Glioblastoma (GBM) is the most common malignant brain tumor in the United States. Incidence of GBM increases with age, and younger age-at-diagnosis is significantly associated with improved prognosis. While the relationship between candidate GBM risk SNPs and age-at-diagnosis has been explored, geno...

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Vydáno v:Int J Cancer
Hlavní autoři: Ostrom, Quinn T., Kinnersley, Ben, Armstrong, Georgina, Rice, Terri, Chen, Yanwen, Wiencke, John K., McCoy, Lucie S., Hansen, Helen M., Amos, Christopher I., Bernstein, Jonine L., Claus, Elizabeth B., Eckel-Passow, Jeanette E., Il’yasova, Dora, Johansen, Christoffer, Lachance, Daniel H., Lai, Rose K., Merrell, Ryan T., Olson, Sara H., Sadetzki, Siegal, Schildkraut, Joellen M., Shete, Sanjay, Rubin, Joshua B., Andersson, Ulrika, Rajaraman, Preetha, Chanock, Stephen J., Linet, Martha S., Wang, Zhaoming, Yeager, Meredith, Houlston, Richard S., Jenkins, Robert B., Wrensch, Margaret R., Melin, Beatrice, Bondy, Melissa L., Barnholtz-Sloan, Jill. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205887/
https://ncbi.nlm.nih.gov/pubmed/30152087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31759
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