Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21

Incidence of glioma is approximately 50% higher in males. Previous analyses have examined exposures related to sex hormones in women as potential protective factors for these tumors, with inconsistent results. Previous glioma genome-wide association studies (GWAS) have not stratified by sex. Potenti...

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Publicado en:Sci Rep
Autores principales: Ostrom, Quinn T., Kinnersley, Ben, Wrensch, Margaret R., Eckel-Passow, Jeanette E., Armstrong, Georgina, Rice, Terri, Chen, Yanwen, Wiencke, John K., McCoy, Lucie S., Hansen, Helen M., Amos, Christopher I., Bernstein, Jonine L., Claus, Elizabeth B., Il’yasova, Dora, Johansen, Christoffer, Lachance, Daniel H., Lai, Rose K., Merrell, Ryan T., Olson, Sara H., Sadetzki, Siegal, Schildkraut, Joellen M., Shete, Sanjay, Rubin, Joshua B., Lathia, Justin D., Berens, Michael E., Andersson, Ulrika, Rajaraman, Preetha, Chanock, Stephen J., Linet, Martha S., Wang, Zhaoming, Yeager, Meredith, Houlston, Richard S., Jenkins, Robert B., Melin, Beatrice, Bondy, Melissa L., Barnholtz-Sloan, Jill. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943590/
https://ncbi.nlm.nih.gov/pubmed/29743610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24580-z
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