Age-specific genome-wide association study in glioblastoma identifies increased proportion of ‘lower grade glioma’-like features associated with younger age

Glioblastoma (GBM) is the most common malignant brain tumor in the United States. Incidence of GBM increases with age, and younger age-at-diagnosis is significantly associated with improved prognosis. While the relationship between candidate GBM risk SNPs and age-at-diagnosis has been explored, geno...

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Publicat a:Int J Cancer
Autors principals: Ostrom, Quinn T., Kinnersley, Ben, Armstrong, Georgina, Rice, Terri, Chen, Yanwen, Wiencke, John K., McCoy, Lucie S., Hansen, Helen M., Amos, Christopher I., Bernstein, Jonine L., Claus, Elizabeth B., Eckel-Passow, Jeanette E., Il’yasova, Dora, Johansen, Christoffer, Lachance, Daniel H., Lai, Rose K., Merrell, Ryan T., Olson, Sara H., Sadetzki, Siegal, Schildkraut, Joellen M., Shete, Sanjay, Rubin, Joshua B., Andersson, Ulrika, Rajaraman, Preetha, Chanock, Stephen J., Linet, Martha S., Wang, Zhaoming, Yeager, Meredith, Houlston, Richard S., Jenkins, Robert B., Wrensch, Margaret R., Melin, Beatrice, Bondy, Melissa L., Barnholtz-Sloan, Jill. S.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205887/
https://ncbi.nlm.nih.gov/pubmed/30152087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31759
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